https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 Medication Discrepancies and Regimen Complexity in Decompensated Cirrhosis: Implications for Medication Safety https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45123 Wed 26 Oct 2022 16:14:20 AEDT ]]> Paclitaxel and Therapeutic Drug Monitoring with Microsampling in Clinical Practice https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:54540 Tue 27 Feb 2024 20:42:11 AEDT ]]> The multi-functional calcium/calmodulin stimulated protein kinase (CaMK) family: emerging targets for anti-cancer therapeutic intervention https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44961 2+ signalling in key events of cancer cell function and tumour progression, such as proliferation, migration, invasion and survival, has recently begun to be appreciated. Many cellular Ca²⁺-stimulated signalling cascades utilise the intermediate, calmodulin (CaM). The Ca²⁺/CaM complex binds and activates a variety of enzymes, including members of the multifunctional Ca²⁺/calmodulin-stimulated protein kinase (CaMK) family. These enzymes control a broad range of cancer-related functions in a multitude of tumour types. Herein, we explore the cancer-related functions of these kinases and discuss their potential as targets for therapeutic intervention.]]> Tue 25 Oct 2022 13:45:27 AEDT ]]> Combined In Silico and In Vitro Evidence Supporting an Aurora A Kinase Inhibitory Role of the Anti-Viral Drug Rilpivirine and an Anti-Proliferative Influence on Cancer Cells https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51615 Tue 12 Sep 2023 13:50:05 AEST ]]> Potential use of antimicrobial peptides as vaginal spermicides/microbicides https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24732 in vivo in mice. Therefore, the availability of LL-37 as a vaginal spermicide/microbicide will empower women for self-protection against unwanted pregnancies and STI.]]> Thu 17 Feb 2022 09:27:51 AEDT ]]>